clinical evaluation of drug induced acute angle closure glaucoma

purpose: to evaluate all cases of drug induced angle closure glaucoma cases who presented to feiz hospital, isfahan during 2008-2010. case report: in this retrospective case series, we present 7 cases of drug induced angle closure glaucoma after administration of topiramate. all patients were female. the average age of patients was 33.28 years old (ranging from 19 to 44). with sufficient corneal clarity, mean bcva was 20/400 and mean refractive error was -6.50 (rang -3.00 to-12.00) diopters. mean intraocular pressure was 44.71 (rang 34 to 60) mmhg. mean time normalization of intraocular pressure was 12.30 (rang 8 to 23) hours. conclusion: acute myopia and acute angle closure glaucoma are serious adverse effects of topiramate, both of which are reversible with immediate discontinuation of the drug. so, taking a complete drug history and thinking about culprit drugs is critical in the evaluation of such cases.